C – Coloboma of the eye, central nervous system anomalies
H – Heart defects
A – Atresia of the choanae
R – Retardation of growth and/or development
G – Genital and/or urinary defects (hypogonadism, undescended testicles, besides hypospadias)
E – Ear anomalies and/or deafness and abnormally bowl-shaped and concave ears, known as “lop ears”.